Characteristic | Details |
---|---|
Chemical Name | Bromhexine Hydrochloride |
Molecular Formula | C14H20Br2N2 |
Dosages | 4 mg, 8 mg, 16 mg |
Administration Route | Oral, Intravenous |
Half-Life | 12 hours |
Therapeutic Class | Mucolytic |
More about Bromhexine |
Pharmacokinetics
Bromhexine Hydrochloride 8 mg showcases a rapid absorption profile. Its bioavailability, influenced by first-pass metabolism, remains approximately 20%. Following administration, peak plasma concentrations are reached in one hour. The drug displays significant tissue distribution, permeating into lung tissues effectively. The elimination half-life extends up to 12 hours. This prolonged presence supports its therapeutic action. Bromhexine undergoes extensive hepatic metabolism. It transforms into various metabolites, contributing to its efficacy. The excretion process is primarily renal. Almost 85% of the dose appears in the urine over a span of 24 hours. These pharmacokinetic properties render Bromhexine a potent mucolytic agent.
Other Uses for Bromhexine
Beyond its role as a mucolytic, Bromhexine Hydrochloride 4 mg demonstrates potential in adjunctive therapy. In respiratory disorders, it enhances the penetration of antibiotics into bronchial secretions. Its efficacy extends to chronic obstructive pulmonary disease (COPD) management. The drug contributes to reduced exacerbation frequency. Bromhexine’s role in pediatric care involves easing cough symptoms in upper respiratory tract infections. Investigations into its utility in treating cystic fibrosis suggest potential benefits. However, comprehensive studies remain essential. Bromhexine’s versatility underlines its relevance in diverse clinical scenarios.
Warning & Precautions
Employ caution with Bromhexine Hydrochloride 16 mg in patients with peptic ulcer disease. Gastric mucosa irritation may occur. Monitor individuals with compromised renal or hepatic function closely. Adjustments to dosage may be necessary. Concurrent administration with certain antibiotics requires supervision. Potential for enhanced absorption exists. Bromhexine’s mucolytic activity may affect asthma control adversely. Ensure that bronchial hyperreactivity is under control prior to initiation. Pregnant and lactating women should consult healthcare providers. The drug’s safety profile during pregnancy lacks extensive research.
Missed Dose
In instances of a missed Bromhexine Hydrochloride 8 mg dose, take the medication promptly. However, if the subsequent dose is imminent, skip the missed dose. Avoid doubling up doses. Consistency in administration supports effective treatment outcomes. Regular dosing intervals enhance therapeutic efficacy. For any concerns regarding missed doses, consultation with a healthcare provider is advisable. Maintaining a structured dosing schedule is crucial in managing symptoms effectively. Patients are encouraged to set reminders to prevent missed doses.
Side Effects
Common side effects of Bromhexine Hydrochloride 4 mg include gastrointestinal disturbances. Nausea, diarrhea, and gastric discomfort may occur. Allergic reactions, though rare, warrant immediate medical attention. Signs include rash, itching, or swelling. Report any respiratory difficulty promptly. Headache and dizziness present occasionally. These symptoms generally subside without intervention. Long-term use may necessitate liver function monitoring. Bromhexine’s safety profile remains favorable with proper usage. Patients should report adverse effects to their healthcare provider.
Bromhexine for Sale Online
The availability of Bromhexine Hydrochloride 16 mg online facilitates access for patients. Various pharmaceutical platforms offer the medication. Adhere to licensed and reputable sources for purchase. Ensure compliance with regulatory guidelines. An online purchase provides convenience, particularly for those with mobility challenges. Verify the authenticity of the product before acquisition. Proper storage conditions preserve efficacy. Secure transactions ensure safe procurement. The digital age enables broader access to essential medications, including Bromhexine. For more detailed information, refer to PubChem.
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